Stop Guessing Your Sample Size
Instantly calculate precise sample size requirements for any clinical study.
Manually determining sample sizes means juggling complex formulas, protocol variations, and regulatory demands. One small error can derail timelines or invalidate results. You waste hours double-checking calculations and documenting assumptions.
A Sample Size Calculation Agent for Biostatisticians is an AI-powered agent that helps biostatisticians determine exact sample size needs for clinical studies by analyzing study parameters and statistical requirements, enabling confident, audit-ready decisions.
What this replaces
The hidden cost
What this is really costing you
Calculating sample size for clinical studies requires careful consideration of study design, endpoints, power, and error rates. Each protocol change forces you to recalculate, document, and justify your numbers. Manual calculations introduce risk of error and eat into time needed for deeper analysis.
Time wasted
1.8 hrs/week
Every week, burned on work an AI agent handles in minutes.
Money lost
$2,610/year
In salary, missed revenue, and operational drag — annually.
If you keep ignoring it
Manual errors or missed assumptions can lead to underpowered studies, regulatory setbacks, or costly protocol amendments.
Cost estimates derived from U.S. Bureau of Labor Statistics occupational wage data and O*NET task analysis.
Return on investment
The math speaks for itself
Today — without agent
1.8 hrs/week
of manual work
With your AI agent
0.4 hrs/week
agent-handled
You save
$2,030/year
every year, reinvested into growing your business
Estimates based on U.S. Bureau of Labor Statistics median salary data and O*NET task importance ratings from worker surveys. Time savings assume 80% automation of eligible task components.
Jobs your agent handles
What this agent does for you
Complete jobs, handled end-to-end — so your team focuses on what matters.
Quick Calculation for New Study
You ask your agent to calculate the sample size for a two-arm superiority trial with 80% power and a 5% significance level.
Protocol Amendment Support
You ask your agent to recalculate sample size after a protocol change affecting the primary endpoint.
Regulatory Submission Prep
You ask your agent to generate a justification summary and assumptions table for inclusion in your protocol document.
Scenario Planning
You ask your agent to compare sample size requirements for varying dropout rates and effect sizes to inform study design decisions.
How to hire your agent
Connect your tools
Link your existing data analysis, clinical trials database, and documentation tools used for protocol development and statistical planning.
Tell your agent what you need
Type: 'Calculate the sample size for a three-arm non-inferiority trial with 90% power, 2% significance, and expected dropout rate of 10%.'
Agent gets it done
Receive a precise sample size calculation, a summary of assumptions, and ready-to-use justification text for your protocol or report.
You doing it vs. your agent doing it
Agent skill set
What this agent knows how to do
Automated Sample Size Calculation
This agent calculates required sample sizes based on your specified study design, endpoints, power, and significance level, returning a clear numeric output.
Protocol-Specific Adjustments
This agent adjusts calculations for stratification, multiple arms, or non-inferiority designs, providing tailored sample size recommendations for your study type.
Assumption Documentation
This agent generates a summary of all assumptions and parameters used in the calculation, ready for inclusion in protocols or regulatory submissions.
Justification Text Generation
This agent writes clear, audit-ready justification text explaining the sample size rationale, suitable for protocols and statistical analysis plans.
Scenario Comparison
This agent compares sample size requirements across multiple scenarios (e.g., different effect sizes or dropout rates) and presents the results in a table.
Key capabilities
- Automates Automated Sample Size Calculation: This agent calculates required sample sizes based on your specified study design, endpoints, power, and significance level, returning a clear numeric output.
- Automates Protocol-Specific Adjustments: This agent adjusts calculations for stratification, multiple arms, or non-inferiority designs, providing tailored sample size recommendations for your study type.
- Automates Assumption Documentation: This agent generates a summary of all assumptions and parameters used in the calculation, ready for inclusion in protocols or regulatory submissions.
- Automates Justification Text Generation: This agent writes clear, audit-ready justification text explaining the sample size rationale, suitable for protocols and statistical analysis plans.
- Automates Scenario Comparison: This agent compares sample size requirements across multiple scenarios (e.
AI Agent FAQ
The agent uses industry-standard statistical methods and double-checks calculations against your provided parameters. You can review all assumptions and outputs before finalizing results.
The agent supports common designs like superiority, non-inferiority, multiple arms, and stratified studies. For highly specialized or novel designs, manual review is recommended after the agent's output.
The agent generates audit-ready calculation summaries and justification text designed for inclusion in protocols and regulatory documents. You should review and edit as needed for your specific submission.
The agent works alongside your existing tools. You provide study parameters manually, and you can export outputs for use in your preferred software.
You can specify power, significance level, effect size, dropout rate, and other key parameters. The agent documents all assumptions in the output for transparency.
Related tasks
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